This study investigated all-around pathways and methods of reforming laboratory animal science education in the new era. With the rapid advancement of life sciences, traditional laboratory animal science curricula have shown their limitations, failing to keep up with current research practices and satisfy the increasingly stringent demands for animal welfare and ethics. This paper provides an in-depth analysis of existing challenges in teaching and proposes a "trinity" reform model, with animal welfare ethics as the core, virtual simulation technology as support, and management and assessment system innovation as the driving force. This framework aims not only to improve teaching efficiency and quality but also to cultivate students with innovative thinking, strong practical skills, and a sense of professional ethics. In the end, this study gives a forward-looking and actionable solution for the systematic reform of laboratory animal science curricula in higher education institutions.
Keywords: Laboratory animal science, Teaching reform, Virtual simulation, Animal welfare ethics, 3R principles, Curriculum-based ideological and political education, Blended learning

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