Ziyue Li¹, Bailong Hu², Xiaohua Zou²

¹College of Anesthesiology, Guizhou Medical University, Guizhou 550004, China. ²Department of Anesthesiology, the Affiliated Hospital of Guizhou Medical University, Guizhou 550004, China. 

Address correspondence to: Bailong Hu, Department of Anesthesiology, the Affiliated Hospital of Guizhou Medical University, NO. 28 Guiyi Street, Guiyang 550004, Guizhou, China. Phone number: +86-15185184309; E-mail: hubailong@gmc.edu.cn. Xiaohua Zou, Department of Anesthesiology, the Affiliated Hospital of Guizhou Medical University, NO. 28 Guiyi Street, Guiyang 550004, Guizhou, China. Tel: +86-13809416036; Fax: +86-851-86771013; E-mail: zouxiaohuazxh@gmc.edu.cn.

Acknowledgement: This work was supported by the National Natural Science Foundation of China (No. 82160951, 82160224), the project of Guiyang Science and Technology Plan (zhukehe[2024]-2-27), the Cultivate project 2021 for National Natural Science Foundation of China, the Affiliated Hospital of Guizhou Medical University (gyfynsfc-2021-35, gyfynsfc-2021-49).

DOI: https://doi.org/10.61189/434706ysltap

Received December 5, 2023; Accepted February 4, 2024; Published June 30, 2024

Highlights 

Currently, ischemic heart disease ranks as the most prevalent form of primary heart disease. The risk of myocardial ischemia-reperfusion injury, along with its associated mortality, is notably rising among perioperative patients. Recognizing the underlying mechanisms of myocardial ischemia-reperfusion injury and identifying suitable treatments are crucial. Inhibitors targeting the key molecules involved in pyroptosis hold promise as potential therapeutic options for managing myocardial ischemia-reperfusion injury

Chenglong Zhu^1,3*, Miao Zhou^1,4*, Yongchu Hu², Wenyun Xu², Zui Zou^1,2

¹School of Anesthesiology, Naval Medical University, Shanghai 200433, China. ²Department of Anesthesiology, Second Affiliated Hospital of Naval Medical University, Shanghai 200003, China. ³Faculty of Anesthesiology, Changhai Hospital, Naval Medical University, Shanghai 200433, China. ⁴Department of Anesthesiology, the Affiliated Cancer Hospital of Nanjing Medical University, Jiangsu Cancer Hospital, Jiangsu Institute of Cancer Research, Nanjing Medical University, Nanjing 210009, Jiangsu, China. 

*The authors have contributed equally to this work. 

Address correspondence to: Zui Zou, School of Anesthesiology, Naval Medical University, 168 Changhai Road, Yangpu District, Shanghai 200433, China. Email: zouzui@smmu.edu.cn. Wenyun Xu, Second Affiliated Hospital of Naval Medical University, 415 Fengyang Road, Huangpu District, Shanghai 200003, China. Email: xuwenyun@ smmu.edu.cn.

Acknowledgement: This study was funded by the National Natural Science Foundation of China (81670072), the Shanghai Municipal Committee of Science and Technology (20XD1434400) and Special Project on Incubation of Civil-Military Integration Achievements of the Naval Medical University (2022-RH10). Declaration of conflict of interest: None. 

Ethics approval and consent to participate: Chinese Clinical Trial Registry approved this study (ChiCTR2200060783). All procedures and research activities performed in the study were in accordance with the ethical standards of the institutional research committee. Consent was obtained from a legally authorized representative. 

DOI: https://doi.org/10.61189/109678mkmeds

Received November 29, 2023; Accepted January 16, 2024; Published June 30, 2024

Highlights 

● SEEK^flex (Safe Easy Endotracheal Kit-flexible) is a modified introducer, which provides a simple and rapid way for intubating patients with laryngeal tumors. 

● With its non-invasive and gentle approach, SEEK^flex minimizes patient discomfort, enhancing the overall patient experience. 

● Flexible fiberoptic bronchoscope remains the most frequently used tool for managing difficult airways.

Huanjia Xue^1,3, Shengze Yang^2,3, Guangkuo Ma^1,3, Ziwei Xia^1,3, Liwei Wang^1,3, Kai Wang ^1,3

¹Xuzhou Clinical College, ²School of Anesthesiology, Xuzhou Medical University, Xuzhou 221009, China. ³Department of Anesthesiology, Xuzhou Central Hospital, Xuzhou 221009, China.

Address correspondence to: Kai Wang, Department of Anesthesiology, Xuzhou Central Hospital, No.199 Jiefang South Road, Quanshan District, Xuzhou 221009, Jiangsu, China. Tel: 18112012729. E-mail: wangkaistream99@ xzhmu.edu.cn.

Acknowledgement: This work was supported by Young Scientist Fund of National Natural Science Foundation of China (81700078) and Xuzhou Medical Key Talents program (XWRCHT20220051).

DOI: https://doi.org/10.61189/601268tfpowt

Received November 5, 2023; Accepted January 30, 2024; Published June 30, 2024

Highlights

● Foot and ankle arthroscopic techniques are vital for diagnosing and treating foot and ankle disorders.

● Ultrasound-guided nerve blocks in the foot and ankle provide precise nerve selection.

Yangmengna Gao^1,2, Ran Yuan^1,2, Kecheng Zhai^1,2, Hui Su^1,2, Renke Sun^1,2, Shangping Fang^1,2 

¹School of Anesthesiology, ²Anesthesia Laboratory and Training Center, Wannan Medical College, Wuhu 241002, Anhui, China. 

Address correspondence to: Shangping Fang, Anaesthesiology Experimental Training Center, College of Anesthesiology, Wannan Medical College, No.22 Wenchang West Road, Yijiang District, Wuhu 241002, Anhui, China. Tel:+86-19855362767. E-mail: 20180041@wnmc.edu.cn.

Acknowledgement: Key Project Research Fund of Wannan Medical College (WK2022Z10); National College Student Innovation and Entrepreneurship Project (202310368016); Anhui Province College Student Innovation and Entrepreneurship Project (S202210368107, S202210368108); Student Research Funding Project of Wannan Medical College (WK2023XS10).

DOI: https://doi.org/10.61189/076009mwdtns

Received January 25, 2024; Accepted March 19, 2024; Published Jane 30, 2024

Highlights 

● Sphingosine 1-phosphate receptor 3 (S1PR3) promotes the proliferation of vascular endothelial cells and enhances barrier function. 

● S1PR3 is a promising target for clinical treatment of cardiac ischemia-reperfusion, cardiac fibrosis and atherosclerosis. 

● Fingolimod and other modulators of S1PR3 have shown therapeutic efficacy in phase I and II clinical trials for cardiovascular diseases. 

● S1PR3 play crucial roles in the perioperative evaluation and treatment of the cardiovascular system, as well as in sepsis.

¹School of Anesthesiology, ²Anesthesia Laboratory and Training Center, Wannan Medical College, Wuhu 241002, China. ³School of Anesthesiology, Department of Anesthetic Pharmacology, Second Military Medical University/Naval Medical University, Shanghai 200433, China. 

Address correspondence to: Shangping Fang, Anesthesia Laboratory and Training Center, School of Anesthesiology, Wannan Medical College, No. 22, Wenchang West Road, Lugang Street, Yijiang District, Wuhu 241002, Anhui, China. Tel: 19855362767; E-mail: 20180041@wnmc.edc.cn.

Acknowledgements: This work was supported by Key Project Research Fund of Wannan Medical College (WK2022Z10) and Research Grant for College Students of Wannan Medical College (WK2022XS26). 

DOI: https://doi.org/10.61189/270899wnwlnz 

Received September 17, 2023; Accepted November 28, 2023; Published March 31, 2024

Highlights 

● The approaches of antioxidant therapy to alleviate sepsis-associated liver injury are summarized from the per spective of oxidative stress in different cells of the liver. 

● Reactive oxygen species, one of the main substances that induce oxidative stress, affects the molecular mecha nism of the relevant signaling pathways. 

 ● Antioxidant therapy is helpful for the recovery of various liver cells in sepsis-associated liver injury and is expect- ed to advance basic and clinical research.

Guangkuo Ma^1,2, Ziwei Xia^1,2, Huanjia Xue^1,2, Hui Wu1,2, Congyou Wu², Liwei Wang^1,2, Kai Wang^1,21Graduate School, Xuzhou Medical University, Xuzhou 221004, Jiangsu, China. ²Department of Anesthesiology, Xuzhou Central Hospital, Xuzhou 221009, Jiangsu, China.Address correspondence to: Kai Wang, Department of Anesthesiology, Xuzhou Central Hospital, No. 199 Jiefang South Road, Quanshan District, Xuzhou 221009, Jiangsu, China. Tel: 18112012729. E-mail: wangkaistream99@ xzhmu.edu.cn.

Acknowledgement: This work was supported by the Department of Anesthesiology of Xuzhou Central Hospital. DOI: https://doi.org/10.61189/526064kphcum Received November 1, 2023; Accepted November 28, 2023; Published March 31, 2024Highlights● Maintaining anesthesia depth within speciffc ranges, as indicated by electroencephalography monitors, may reduce the risk of postoperative cognitive dysfunction.● Quantitative analysis of electroencephalography data can provide insights into the characteristics of postoperative cognitive dysfunction, aiding in its early detection and diagnosis.● Combining electroencephalography with functional magnetic resonance imaging may enhance the assessment of brain function and improve the accuracy of monitoring devices.

Mayura Thilanka Iddagoda^1,2, Christopher Etherton-Beer^1,2, Leon Flicker^1,21Perioperative Medical Service, Royal Perth Hospital, Perth, Western Australia 6000, Australia. ²School of Medicine, University of Western Australia, Perth, Western Australia 6000, Australia.Address correspondence to: Mayura Thilanka Iddagoda, Perioperative Medical Service, Royal Perth Hospital, Wellington Street, Perth, Western Australia 6000, Australia. Phone: +61 8 9224 2244; Email: Mayura.Iddagoda@ health.wa.gov.au.

Acknowledgement: Royal Australasian College of Physicians (Research Entry Scholarship).DOI: https://doi.org/10.61189/956852bomilz Received October 23, 2023; Accepted November 21, 2023; Published March 31, 2024Highlights● Iron deffciency is the commonest cause for anaemia in patients undergoing surgeries, and this review summarizes its implications.

● Intravenous iron is a better treatment option for iron deffciency than other iron preparations.● Body iron metabolism is a complex process, and evidence is confficting on iron supplementation in surgical patients.● Intravenous iron replacement, as a part of patient blood management, has shown benefft in perioperative anaemia.

Wen-Hui Guo^1,*, Qing-Lai Zang^2,*, Bing Xu¹, Tian-Ying Xu¹, Zhan-Heng Chen¹, Miao Zhou³

¹School of Anesthesiology, Second Military Medical University/Naval Medical University, Shanghai 200433, China. ²Department of Anesthesiology, Second Affiliated Hospital of Naval Medical University, Shanghai 200003, China. ³Department of Anesthesiology, the Affiliated Cancer Hospital of Nanjing Medical University, Jiangsu Cancer Hospital, Jiangsu Institute of Cancer Research, Nanjing Medical University, Nanjing 210009, Jiangsu, China.

^*The authors contribute equally.

Address correspondence to: Zhan-Heng Chen, School of Anesthesiology, Second Military Medical University/Naval Medical University, 800 Xiangyin Road, Shanghai 200433, China. Tel: +86 21 81872034. E-mail: chenzhanheng17@mails.ucas.ac.cn; Miao Zhou, Department of Anesthesiology, the Affiliated Cancer Hospital of Nanjing Medical University, Jiangsu Cancer Hospital, Jiangsu Institute of Cancer Research, Nanjing Medical University, Nanjing 210009, Jiangsu, China. Tel: +86 18217567295. E-mail: zhoumiao@jszlyy.com.cn.

Acknowledgment: This work was supported by the National Natural Science Foundation of China (62002297, 62073225, and 61836005), the Science and Technology Commission of Shanghai Municipality (20XD1434400), the Talent Development Fund of Shanghai (2020075), the Medical-Engineering Cross Fund of Shanghai Jiao Tong University (YG2022QN043), and the Guangxi Science and Technology Base and Talent Special Project (2021AC19394). The authors would like to thank all the guest editors and anonymous reviewers for their constructive advice.

DOI: https://doi.org/10.61189/536468bkwzzn

Received July 21, 2023; Accepted November 15, 2023; Published March 31, 2024

Highlights

● This review introduces the core concepts of artificial intelligence (AI) and describes the most commonly encountered computerized functioning of AI in anesthesiology.

● This survey systematically presents the main clinical applications of AI in anesthesia and perioperative medicine according to the perioperative phases.

● The advantages and disadvantages of introducing AI into the medical field are also discussed to explore the career development direction of anesthesiologists in the future.

Qin Yin^1,*, Jinfeng Wang^2,*, Shu Wang³, Yu'e Sun⁴, Wei Cheng^1,5, Yinming Zeng¹

¹Department of Pain Clinic, The Affiliated Hospital of Xuzhou Medical University, Xuzhou 221000, China. ²Department of Anesthesiology, Xuzhou Central Hospital, Xuzhou 221000, China. ³Department of Anesthesiology, Yancheng Third People's Hospital, Yancheng 224000, China. ⁴Department of Anesthesiology, Nanjing Drum Tower Hospital, The Affiliated Hospital of Nanjing University Medical School, Nanjing 210000, China. ⁵Department of Anesthesiology, Huai'an First People's Hospital Affiliated to Nanjing Medical University, Huai'an 223000, China.

*The authors contribute equally.

Address correspondence to: Yinming Zeng, Department of Anesthesiology, The Affiliated Hospital of Xuzhou Medical University, No.99 West Huaihai Road, Xuzhou 221000, China. E-mail: xzkj2297@163.com. Wei Cheng, Department of Anesthesiology, Huai’an First People’s Hospital Affiliated to Nanjing Medical University, No.1 West Yellow River Road, Huai’an 223000, China/Department of Anesthesiology, The Affiliated Hospital of Xuzhou Medical University, No.99 West Huaihai Road, Xuzhou 221000, China. E-mail: hayyyzxx@163.com. 

DOI: https://doi.org/10.61189/657934sjvovo

Received August 12, 2023; Accepted November 28, 2023; Published December 31, 2023

Highlights

● Complains of sleepless and tinnitus are common in sleep clinics, which is a different type of sleep disorder. In this article, we first summarize this disorder, which is defined as thyroid disease-related sleep disorder (TSD), and propose to categorize it as insomnia secondary to a somatic disorder.

● We have attempted to provide some preliminary diagnostic and therapeutic recommendations for TSD.

● In the treatment of TSD, we suggest relying on the theory of integrating Chinese and Western medicine, emphasizing holistic diagnosis and treatment, and precise medication.

Yunfei Hao^1,*, Haoyan Lou^1,*, Jingnuo Jiang¹, Wenhui Guo²,  Zhanheng Chen², Bing Xu²

¹College of Basic Medicine, Second Military Medical University/Naval Medical University, Shanghai 200433, China. ²School of Anesthesiology, Second Military Medical University/Naval Medical University, Shanghai 200433, China. 

*The authors contribute equally.

Address correspondence to: Wenhui Guo, School of Anesthesiology, Second Military Medical University/Naval Medical University, No.800 Xiangyin Road, Shanghai 200433, China. E-mail: wendyguo17@outlook.com; Zhanheng Chen, School of Anesthesiology, Second Military Medical University/Naval Medical University, No.800 Xiangyin Road, Shanghai 200433, China. E-mail: chenzhanheng17@mails.ucas.ac.cn; Bing Xu, School of Anesthesiology, Second Military Medical University/Naval Medical University, No.800 Xiangyin Road, Shanghai 200433, China. E-mail: xubing1992@smmu.edu.cn.

DOI: https://doi.org/10.61189/284605tsowfy

Received September 26, 2023; Accepted November 28, 2023; Published December 31, 2023

Highlights

● General anesthetics may cause neurotoxicity.

● Single general anesthesia before 3 years of age does not affect cognitive function in pediatric patients.

● The effect of general anesthetics on the cognitive function of pediatric patients is related to the number of anesthesia sessions, duration and the depth of anesthetic exposure.

Chenglong Zhu^1,3*, Miao Zhou^1,4*, Yongchu Hu², Wenyun Xu², Zui Zou^1,2

¹School of Anesthesiology, Naval Medical University, Shanghai 200433, China. ²Department of Anesthesiology, Second Affiliated Hospital of Naval Medical University, Shanghai 200003, China. ³Faculty of Anesthesiology, Changhai Hospital, Naval Medical University, Shanghai 200433, China. ⁴Department of Anesthesiology, the Affiliated Cancer Hospital of Nanjing Medical University, Jiangsu Cancer Hospital, Jiangsu Institute of Cancer Research, Nanjing Medical University, Nanjing 210009, Jiangsu, China. 

*The authors have contributed equally to this work. 

Address correspondence to: Zui Zou, School of Anesthesiology, Naval Medical University, 168 Changhai Road, Yangpu District, Shanghai 200433, China. Email: zouzui@smmu.edu.cn. Wenyun Xu, Second Affiliated Hospital of Naval Medical University, 415 Fengyang Road, Huangpu District, Shanghai 200003, China. Email: xuwenyun@ smmu.edu.cn.

Acknowledgement: This study was funded by the National Natural Science Foundation of China (81670072), the Shanghai Municipal Committee of Science and Technology (20XD1434400) and Special Project on Incubation of Civil-Military Integration Achievements of the Naval Medical University (2022-RH10). Declaration of conflict of interest: None. 

Ethics approval and consent to participate: Chinese Clinical Trial Registry approved this study (ChiCTR2200060783). All procedures and research activities performed in the study were in accordance with the ethical standards of the institutional research committee. Consent was obtained from a legally authorized representative. 

DOI: https://doi.org/10.61189/109678mkmeds

Received November 29, 2023; Accepted January 16, 2024; Published June 30, 2024

Highlights 

● SEEK^flex (Safe Easy Endotracheal Kit-flexible) is a modified introducer, which provides a simple and rapid way for intubating patients with laryngeal tumors. 

● With its non-invasive and gentle approach, SEEK^flex minimizes patient discomfort, enhancing the overall patient experience. 

● Flexible fiberoptic bronchoscope remains the most frequently used tool for managing difficult airways.

Yangmengna Gao^1,2, Ran Yuan^1,2, Kecheng Zhai^1,2, Hui Su^1,2, Renke Sun^1,2, Shangping Fang^1,2 

¹School of Anesthesiology, ²Anesthesia Laboratory and Training Center, Wannan Medical College, Wuhu 241002, Anhui, China. 

Address correspondence to: Shangping Fang, Anaesthesiology Experimental Training Center, College of Anesthesiology, Wannan Medical College, No.22 Wenchang West Road, Yijiang District, Wuhu 241002, Anhui, China. Tel:+86-19855362767. E-mail: 20180041@wnmc.edu.cn.

Acknowledgement: Key Project Research Fund of Wannan Medical College (WK2022Z10); National College Student Innovation and Entrepreneurship Project (202310368016); Anhui Province College Student Innovation and Entrepreneurship Project (S202210368107, S202210368108); Student Research Funding Project of Wannan Medical College (WK2023XS10).

DOI: https://doi.org/10.61189/076009mwdtns

Received January 25, 2024; Accepted March 19, 2024; Published Jane 30, 2024

Highlights 

● Sphingosine 1-phosphate receptor 3 (S1PR3) promotes the proliferation of vascular endothelial cells and enhances barrier function. 

● S1PR3 is a promising target for clinical treatment of cardiac ischemia-reperfusion, cardiac fibrosis and atherosclerosis. 

● Fingolimod and other modulators of S1PR3 have shown therapeutic efficacy in phase I and II clinical trials for cardiovascular diseases. 

● S1PR3 play crucial roles in the perioperative evaluation and treatment of the cardiovascular system, as well as in sepsis.

Yue Wang¹, Miao Zhou¹, Pengxin Li², Lianbing Gu²

¹Department of Anesthesiology, The Affiliated Cancer Hospital of Nanjing Medical University, Jiangsu Cancer Hospital, Jiangsu Institute of Cancer Research, Nanjing Medical University, Nanjing 210009, Jiangsu, China. ²Xuzhou Medical University, Jiangsu Province Key Laboratory of Anesthesiology, Jiangsu Province Key Laboratory of Anesthesia and Analgesia Application Technology, Xuzhou 221002, Jiangsu, China.

Address correspondence to: Lianbing Gu, The Affiliated Cancer Hospital of Nanjing Medical University, Department of Anesthesiology, Jiangsu Cancer Hospital, Jiangsu Institute of Cancer Research, Nanjing Medical University, Nanjing 210009, Jiangsu, China. E-mail: 13951947684@163.com.

Received March 15, 2023; Accepted April 27, 2023; Published June 30, 2023

DOI: https://doi.org/10.61189/343605tjncke

Highlights

● This review focuses on literature regarding end-tidal carbon dioxide monitoring for non-intubated patients.

● Partial pressure of carbon dioxide monitoring can benefit non-intubated patients.

● As carbon dioxide detection technology continues to improve, end-tidal carbon dioxide monitoring is expected to be used in more medical scenarios.

Zhezhe Fan¹, Zhanheng Chen², Saluj Dev Luitel^3,4, Bing Xu²

¹College of Basic Medicine, Second Military Medical University/Naval Medical University, Shanghai 200433, China. ²School of Anesthesiology, Second Military Medical University/Naval Medical University, Shanghai 200433, China. ³Foreign Training Group, Second Military Medical University/Naval Medical University, Shanghai 200433, China. ⁴College of Medicine, Nepalese Army Institute of Health Sciences, Kathmandu 44600, Nepal.

Address correspondence to: Bing Xu, School of Anesthesiology, Naval Medical University, 800 Xiangyin Road, Shanghai 200433, China. Tel: +86 21 81872030. E-mail: mzxubing1992@163.com.

Received February 27, 2023; Accepted March 31, 2023; Published June 30, 2023DOI: https://doi.org/10.61189/298294zwziab

Highlights

● Ultrasound-guided radial artery catheterization can effectively improve the success rate of first-time puncture and reduce the total puncture time and the incidence of complications.

● Ultrasound-guided radial artery catheterization methods should be selected based on the specific characteristics of individual patients.

Lize Xiong

Shanghai Key Laboratory of Anesthesiology and Brain Functional Modulation, Clinical Research Center for An-esthesiology and Perioperative Medicine, Translational Research Institute of Brain and Brain-Like Intelligence, Shanghai Fourth People's Hospital, School of Medicine, Tongji University, Shanghai 200434, China.

Published June 30, 2023DOI: https://doi.org/10.61189/064156dduwdo

Jinjing Wu^1,*, Yang Yuan^2,*, Long Liu¹, Haipo Cui¹, Tianying Xu³, Miao Zhou⁴, Zhanheng Chen³, Bing Xu³

¹School of Health Science and Engineering, University of Shanghai for Science and Technology, Shanghai 200093, China. ²School of Computer Science and Artificial Intelligence, Changzhou University, Jiangsu 213164, China. ³School of Anesthesiology, Second Military Medical University/Naval Medical University, Shanghai 200433, China. ⁴Department of Anesthesiology, the Affiliated Cancer Hospital of Nanjing Medical University, Jiangsu Cancer Hospital, Jiangsu Institute of Cancer Research, Nanjing Medical University, Nanjing 210009, Jiangsu, China. 

^*The authors contribute equally.

Address correspondence to: Haipo Cui, School of Health Science and Engineering, University of Shanghai for Science and Technology, NO.516, Jungong Road, Shanghai 200093, China. E-mail: h_b_cui@163.com, Tel: +86-21-55271290; Bing Xu, School of Anesthesiology, Second Military Medical University/Naval Medical University, 800 Xiangyin Road, Shanghai 200433, China. E-mail: mzxubing1992@163.com, Tel: +86-21-81872030; Zhanheng Chen, School of Anesthesiology, Second Military Medical University/Naval Medical University, 800 Xiangyin Road, Shanghai 200433, China. E-mail: chenzhanheng17@mails.ucas.ac.cn, Tel: +86 21 81872034. 

Received July 19, 2023; Accepted September 6, 2023; Published September 30, 2023

DOI: https://doi.org/10.61189/663074tcakcn

Highlights

● Medical endoscopic images can provide doctors with more accurate, visualized, and three-dimensional views of various internal tissues.

● Image processing techniques such as image denoising, image deblurring, image enhancement, and image segmentation can improve the imaging quality of endoscopes.

Yanchen Lin¹, Ping Li², Jinliang Teng^3,#, Chunhua Liao^4,# 

¹Graduate School, Hebei North University, Hebei 075000, China. ²Graduate School, Wannan Medical College, Anhui 241000, China. ³Department of Anesthesiology, the First Affiliated Hospital of Hebei North University, Hebei 075000, China. ⁴School of Anesthesiology, Second Military Medical University/Naval Medical University, Shanghai 200433, China.

^#Address correspondence to: Chunhua Liao, School of Anesthesiology, Second Military Medical University/Naval Medical University, Shanghai, 200433, China. E-mail: liaochh7@smmu.edu.cn; Jinliang Teng, Department of Anesthesiology, the First Affiliated Hospital of Hebei North University, Hebei 075000, China. E-mail: tengjinliang@126. com.

Received April 6, 2023; Accepted May 18, 2023; Published June 30, 2023

DOI: https://doi.org/10.61189/595412fcjdhw

Highlights

● Patients are at a high risk of fungal infection during perioperative period. 

● MicroRNAs are involved in inflammatory responses, pyroptosis and autophagy in antifungal immunity. 

● MicroRNAs modulate the activation of Th cells during fungal infection, thereby regulating the adaptive immune response. 

● Differentially expressed miRNAs could be used as fungal infection biomarkers.

Yanchen Lin¹, Jing Huang², Ying Zhang¹, Houfeng Li¹, Huixiu Hu¹, Li Tan³

¹Graduate School, Hebei North University, Zhangjiakou 075000, Hebei, China. ²Graduate School, Wannan Medical College, Wuhu 241002, Anhui, China. ³Department of Anesthesiology, Chongqing University Cancer Hospital, Chongqing 400030, China.

Address correspondence to: Li Tan, Department of Anesthesiology, Chongqing University Cancer Hospital, No.181 Hanyu Road, Chongqing 400030, China. E-mail: tanlihh@163.com.

Received August 24, 2023; Accepted September 7, 2023; Published September 30, 2023

DOI: https://doi.org/10.61189/377184mkfywu

Highlights

● The measurement of central venous pressure in patients diagnosed with septic shock does not yield prognostic improvements.

● Central venous pressure measurement in patients with septic shock is associated with prolonged ICU stay. 

● Central venous pressure measurement is not advised for patients diagnosed with septic shock.  

Ziyue Li¹, Bailong Hu², Xiaohua Zou²

¹College of Anesthesiology, Guizhou Medical University, Guizhou 550004, China. ²Department of Anesthesiology, the Affiliated Hospital of Guizhou Medical University, Guizhou 550004, China. 

Address correspondence to: Bailong Hu, Department of Anesthesiology, the Affiliated Hospital of Guizhou Medical University, NO. 28 Guiyi Street, Guiyang 550004, Guizhou, China. Phone number: +86-15185184309; E-mail: hubailong@gmc.edu.cn. Xiaohua Zou, Department of Anesthesiology, the Affiliated Hospital of Guizhou Medical University, NO. 28 Guiyi Street, Guiyang 550004, Guizhou, China. Tel: +86-13809416036; Fax: +86-851-86771013; E-mail: zouxiaohuazxh@gmc.edu.cn.

Acknowledgement: This work was supported by the National Natural Science Foundation of China (No. 82160951, 82160224), the project of Guiyang Science and Technology Plan (zhukehe[2024]-2-27), the Cultivate project 2021 for National Natural Science Foundation of China, the Affiliated Hospital of Guizhou Medical University (gyfynsfc-2021-35, gyfynsfc-2021-49).

DOI: https://doi.org/10.61189/434706ysltap

Received December 5, 2023; Accepted February 4, 2024; Published June 30, 2024

Highlights 

Currently, ischemic heart disease ranks as the most prevalent form of primary heart disease. The risk of myocardial ischemia-reperfusion injury, along with its associated mortality, is notably rising among perioperative patients. Recognizing the underlying mechanisms of myocardial ischemia-reperfusion injury and identifying suitable treatments are crucial. Inhibitors targeting the key molecules involved in pyroptosis hold promise as potential therapeutic options for managing myocardial ischemia-reperfusion injury

Qin Yin^1,*, Jinfeng Wang^2,*, Shu Wang³, Yu'e Sun⁴, Wei Cheng^1,5, Yinming Zeng¹

¹Department of Pain Clinic, The Affiliated Hospital of Xuzhou Medical University, Xuzhou 221000, China. ²Department of Anesthesiology, Xuzhou Central Hospital, Xuzhou 221000, China. ³Department of Anesthesiology, Yancheng Third People's Hospital, Yancheng 224000, China. ⁴Department of Anesthesiology, Nanjing Drum Tower Hospital, The Affiliated Hospital of Nanjing University Medical School, Nanjing 210000, China. ⁵Department of Anesthesiology, Huai'an First People's Hospital Affiliated to Nanjing Medical University, Huai'an 223000, China.

*The authors contribute equally.

Address correspondence to: Yinming Zeng, Department of Anesthesiology, The Affiliated Hospital of Xuzhou Medical University, No.99 West Huaihai Road, Xuzhou 221000, China. E-mail: xzkj2297@163.com. Wei Cheng, Department of Anesthesiology, Huai’an First People’s Hospital Affiliated to Nanjing Medical University, No.1 West Yellow River Road, Huai’an 223000, China/Department of Anesthesiology, The Affiliated Hospital of Xuzhou Medical University, No.99 West Huaihai Road, Xuzhou 221000, China. E-mail: hayyyzxx@163.com. 

DOI: https://doi.org/10.61189/657934sjvovo

Received August 12, 2023; Accepted November 28, 2023; Published December 31, 2023

Highlights

● Complains of sleepless and tinnitus are common in sleep clinics, which is a different type of sleep disorder. In this article, we first summarize this disorder, which is defined as thyroid disease-related sleep disorder (TSD), and propose to categorize it as insomnia secondary to a somatic disorder.

● We have attempted to provide some preliminary diagnostic and therapeutic recommendations for TSD.

● In the treatment of TSD, we suggest relying on the theory of integrating Chinese and Western medicine, emphasizing holistic diagnosis and treatment, and precise medication.