Zhaoyang Yan^1*, Chunhui Qin^2*, Shuya Wang^1*, Zhaohui Xie³, Liyun Kong⁴, Lili Zhong⁵, Hong Wang⁵, Yun Cai⁶, Guohua Jiao⁷, Zhenwei Wang⁸, Qiwen Zhu^9*, Ruoyu Tang^10* 

¹Shanghai Reacool Medical Technology Co., Ltd., Shanghai 200041, China. ²Department of Anesthesiology, Yuey ang Hospital of Integrated Traditional Chinese and Western Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai 200437, China. ³Department of Pain Management, The First Hospital of Lanzhou University, Lanzhou 730000, Gansu Province, China. ⁴Department of Pain Management, The First Affiliated Hospital of Gan nan Medical University, Ganzhou 341000, Jiangxi Province, China. ⁵Department of Anesthesiology and Pain Man agement, Wuhu Fifth People’s Hospital (Anhui Province Wannan Rehabilitation Hospital), Wuhu 241004, Anhui Province, China. ⁶School of Health and Rehabilitation, Nanjing University of Chinese Medicine, Nanjing 210046, Jiangsu Province, China. ⁷Department of Pain Management, Tongxiang Hospital of Traditional Chinese Medicine, Tongxiang 314500, Zhejiang Province, China. ⁸Department of Respiratory Medicine, Yueyang Hospital of Integrat ed Traditional Chinese and Western Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai 200437, China. ⁹Department of Engineering and Computer Science, Syracuse University, New York State/Syra cuse 13210, the United States of America. ¹⁰Department of Psychology, University of British Columbia (UBC), Van couver V6T 1Z4, British Columbia, Canada. 

 *The authors contribute equally.

Address correspondence to: Lili Zhong, Department of Anesthesiology and Pain Management, No. 2, Zhe-Shan East Road, Jinghu District, Wuhu 241004, Anhui Province, China. Tel: +86-180-0963-7377. E-mail: williyia@wnmc.edu.cn. Zhenwei Wang, Department of Respiratory Medicine, No. 110, Ganhe Road, Hongkou District, Shanghai 200437, China. Tel: +86-189-1875-7762. E-mail: wangzhenwei@ shyueyanghospital.com.

Acknowledgement: This project was supported by the research on the application of digital therapy in the treat ment of neuropathic pain caused by herpes zoster (2023yf004) and the Gansu Province Intelligent Pain Diagnosis and Treatment Industry Technology Center. The authors would like to thank all the guest editors and anonymous reviewers for their constructive advice.

DOI: https://doi.org/10.61189/285507yclyaz

Received June 21, 2024; Accepted September 3, 2024; Published December 31, 2024 

Highlights 

 ● Analysis of collected data reveals that digital therapy offer new treatment methods and options in the field of pain management. After conducting research and analysis, it has been found that digital therapeutics offer new treatment methods and options, especially in the area of perioperative pain management. 

 ● Multiple clinical studies indicate that digital therapy has significant effects in the treatment and relief of pain caused by various conditions. 

 ● Domestic and international policies have positively influenced the development and progress of digital therapy. 

 ● Ethical considerations require continuous evaluation, decision-making, and regulation, warranting ongoing reflection. 

 ● Digital therapeutics, as an emerging intervention for pain, are propelling perioperative pain treatment towards a diversified and personalized comprehensive diagnostic and treatment model.