Volume 2, Issue 1

Perioperative medicine is a series of medical activities throughout the perioperative period, including preoperative optimization, intraoperative safety, postoperative rehabilitation, and other activities. Anesthesia is closely integrated with perioperative medicine to guarantee smooth progress of operations, comfortable recovery, and favorable long-term outcome for patients. There are a huge number of clinical data in anesthesia and perioperative medicine, and artificial intelligence (AI) has a powerful ability to analyze and evaluate data; thus, applying AI is a significant advantage in analysis and prediction based on real clinical big data in anesthesia and perioperative medicine. AI has made some progress in the field of anesthesiology and perioperative medicine. This review introduces the most encountered computerized techniques of AI in anesthesiology, main clinical applications themes of AI in anesthesiology, as well as limitations and ethical implications involved in deployment of this technology.

Sepsis is a systemic inflammatory response that caused by infection or trauma, often resulting in multiple organ dysfunction. Its mortality rate is relatively high, ranging between 54% and 68%, and ineffective treatment and poor prognosis pose significant challenges to healthcare in recent years. One of the main pathogeneses of sepsis-induced liver injury is oxidative stress (OS), which refers to a state where the antioxidant system cannot balance oxidative products, leading to the accumulation of excessive oxidative products in the body. When sepsis occurs, the amount of reactive oxygen species produced by the body increases far beyond the levels that can be scavenged by the antioxidant system, thus damaging liver cells and aggravating liver damage. This article introduces the oxidative/antioxidant system, oxidative stress-related pathways, and the molecular mechanism of OS in various types of hepatocytes, with emphasis on the antioxidant treatment on different hepatocytes, in order to understand the mechanism of OS involved in the development and progression of sepsis-associated liver injury. As the research deepens, improving liver function through the treatment of different cells and facilitating related clinical research are expected to provide a new target pathway for the treatment of sepsis-associated liver injury. 

Postoperative cognitive dysfunction (POCD) is a common postoperative complication in elder patients, elevating the risk of dementia, impacting patient prognosis, and adding to the socio-economic burden. Electroencephalography (EEG) enables the recording of brain electrical activity and reffects the state of consciousness. Changes in the electrogram may signal diverse pathological and physiological states. Currently, EEG and its associated monitoring devices are extensively utilized in clinical practice. This paper presents a thorough review of the use of EEG in POCD research, aiming to establish a more substantial foundation for the prediction and prevention of POCD.