Jiaqi Li1,*, Chenglong Zhu1,*, Yan Liao1,*, Xuan Yin1,*, Rui Zhao2 , Changli Wang3, Doblin Sandai4, Haoling Zhang4 , Wangzheqi Zhang1
1School of Anesthesiology, Naval Medical University, Shanghai 200433, China.
2Gansu University of Chinese Medicine, No. 35 Dingxi East Road, Lanzhou 730000, Gansu, China.
3Department of Anesthesiology, Changhai Hospital, Naval Medical University, Shanghai 200433, China.
4Department of Biomedical Sciences, Advanced Medical and Dental Institute, Universiti Sains Malaysia, Penang 13200, Malaysia.
*The authors contribute equally.
Address correspondence to: Doblin Sandai, Department of Biomedical Sciences, Advanced Medical and Dental Institute, Universiti Sains Malaysia, Penang 13200, Malaysia. E-mail: doblin@usm.my. Haoling Zhang, Department of Biomedical Sciences, Advanced Medical and Dental Institute, Universiti Sains Malaysia, Penang 13200, Malaysia. E-mail: zhanghaolingedu@163.com. Wangzheqi Zhang, School of Anesthesiology, Naval Medical University, 800 Xiangyin Road, Yangpu District, Shanghai 200433, China. E-mail: zwzq001031@smmu.edu.cn.
DOI: https://doi.org/10.61189/775612vwvmhm
Received October 3, 2025; Accepted February 28, 2026; Published March 31, 2026
Review Article |Published on: 31 March 2026
[Perioperative Precision Medicine] 2026; 4 (1): 1-43.
Chong Zhou1,2, Xiaoqi Li2, Menglan Hao1,3, Shuqing Chang1,2, Jinjing Xia1,2,3
1University of Shanghai for Science and Technology, Shanghai 200093, China.
2Shanghai Chest Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200030, China.
3Shanghai Jiao Tong University, Shanghai 200030, China.
Address correspondence to: Jinjing Xia, Shanghai Chest Hospital, Shanghai Jiao Tong University School of Medicine, No. 241 Huaihai West Road, Xuhui District, Shanghai 200030, China. E-mail: xjj1099@shchest.org.
DOI: https://doi.org/10.61189/898430njufld
Received October 27, 2025; Accepted December 4, 2025; Published March 31, 2026
Review Article |Published on: 31 March 2026
[Perioperative Precision Medicine] 2026; 4 (1): 44-56
Dezhi Guo1,*, Jingjing Lu2,*, Limin Wei3, Wenyi Wang4
1Department of Anesthesiology, The First Naval Hospital of Southern Theater Command, Zhanjiang 524005, Guangdong, China.
2Clinical College of Traditional Chinese Medicine, Gansu University of Chinese Medicine, Lanzhou 730000, Gansu, China.
3Liaocheng People's Hospital, Liaocheng 252000, Shandong, China.
4Juntendo University, 2-1-1 Hongo, Bunkyo-ku, Tokyo 113-8421, Japan.
*The authors contribute equally.
Address correspondence to: Limin Wei, Liao cheng People's Hospital, No. 67 Dongchang West Road, Dongchangfu District, Liaocheng 252000, Shandong, China. E-mail: weilimin19860914@163.com. Wenyi Wang, Juntendo University, 2-1-1 Hongo, Bunkyo-ku, Tokyo 113-8421, Japan. E-mail: w.wang.mk@juntendo.ac.jp.
DOI: https://doi.org/10.61189/056184yqnaiu
Received December 10, 2025; Accepted February 28, 2026; Published March 31, 2026
Perspective |Published on: 31 March 2026
[Perioperative Precision Medicine] 2026; 4 (1): 57-61
Songxiao Yang1, Ping Zhou2
1Department of Radiation Oncology, The First Affiliated Hospital of Hainan Medical University, Haikou 570100, Hainan, China.
2Radiotherapy Department II, Key Laboratory of Emergency and Trauma of Ministry of Education, The First Affiliated Hospital, The First Clinical College, Hainan Medical University, Haikou 570100, Hainan, China.
Address correspondence to: Ping Zhou, Radiotherapy Department II, Key Laboratory of Emergency and Trauma of Ministry of Education, The First Affiliated Hospital, The First Clinical College, Hainan Medical University, No. 31 Longhua Road, Xinhua District, Haikou 570100, Hainan, China. E-mail: ping.zhou@muhn.edu.cn.
DOI: https://doi.org/10.61189/891717grkkpo
Received December 21, 2025; Accepted March 13, 2026; Published March 31, 2026
Perspective |Published on: 31 March 2026
[Perioperative Precision Medicine] 2026; 4 (1): 62-66
Di Wang, Shafinah Ahmad Suhaimi
Department of Biomedical Sciences, Pusat Kanser Tun Abdullah Ahmad Badawi, Universiti Sains Malaysia, Bertam, Kepala Batas, 13200 Pulau Pinang, Malaysia.
Address correspondence to: Shafinah Ahmad Suhaimi, Department of Biomedical Sciences, Pusat Kanser Tun Abdullah Ahmad Badawi, Universiti Sains Malaysia, Bertam, Kepala Batas, 13200 Pulau Pinang, Malaysia. E-mail: shafinahas@usm.my.
DOI: https://doi.org/10.61189/319254ilybgm
Received December 21, 2025; Accepted March 12, 2026; Published March 31, 2026
Perspective |Published on: 31 March 2026
[Perioperative Precision Medicine] 2026; 4 (1): 67-70
Yutong Sun1,2,3,*, Qin Zhang1,3,*, Yan Zhang2,3,4,*, Sixu Chen2,3,4, Jiayin Wang3,5, Weiqi Lin1,3, Haiyi Qian3,5, Xinyi Xie3,5, Qixiang Xu3,5, Xiaolong Yuan6, Cuifeng Zhang2,3,4
1School of Clinical Medicine, Wannan Medical College, Wuhu 241002, Anhui, China.
2Anesthesia Laboratory and Training Center, Wannan Medical College, Wuhu 241002, Anhui, China.
3Wuhu Perioperative Monitoring and Prognostic Technology Research and Development Center, Wannan Medical College, Wuhu 241002, Anhui, China.
4School of Anesthesiology, Wannan Medical College, Wuhu 241002, Anhui, China.
5School of Pharmacology, Wannan Medical College, Wuhu 241002, Anhui, China.
6The Second Affiliated Hospital of Wannan Medical College, Wuhu 241002, Anhui, China.
*The authors contribute equally and co-first authors.
Address correspondence to: Cuifeng Zhang, School of Anesthesiology, Wannan Medical College, No. 22 Wenchang West Road, Yijiang District, Wuhu 241002, Anhui, China. Tel: +86-15551257181. E-mail: zhangcuifeng@wnmc.edu.cn.
DOI: https://doi.org/10.61189/873111rbsjxe
Received September 5, 2025; Accepted March 3, 2026; Published March 31, 2026
Highlights
● This review presents a comprehensive overview of the pharmacological effects of traditional Chinese medicine (TCM) in sepsisinduced myocardial injury.
● It systematically summarizes the molecular mechanisms and recent research advancements regarding protective effects of TCM in sepsis.
● It proposes a novel "temporal treatment" strategy for Perioperative Sepsis, aligning TCM interventions with the dynamic pathophysiological stages of the disease.
Review Article |Published on: 31 March 2026
[Perioperative Precision Medicine] 2026; 4 (1): 71-93
Yalin Zhu1,2,*, Zhengyu Jiang2,*, Wangzheqi Zhang2,3,*, Jie Huang2, Haoling Zhang4, Haiwen Wang1, Jiafeng Wang2,#, Wen Xu1,#
1Department of Anesthesiology, Naval Hospital of Eastern Theater, Zhoushan 316004, Zhejiang, China.
2Faculty of Anesthesiology, Changhai Hospital, Naval Medical University, Shanghai 200433, China.
3School of Anesthesiology, Naval Medical University, Shanghai 200433, China.
4Department of Biomedical Sciences, Advanced Medical and Dental Institute, Universiti Sains Malaysia, Kepala Batas, Penang, Malaysia.
*The authors contribute equally.
#The authors are co-corresponding authors.
Address correspondence to: Wen Xu, Department of Anesthesiology, Naval Hospital of Eastern Theater, No. 98, Wenhua Road, Dinghai District, Zhoushan 316004, Zhejiang, China. E-mail: xuwennhet@163.com. Jiafeng Wang, Faculty of Anesthesiology, Changhai Hospital, Naval Medical University, No. 168, Changhai Road, Yangpu District, Shanghai 200433, China. E-mail: jfwang@smmu.edu.cn.
DOI: https://doi.org/10.61189/402108pvrojs
Received November 18, 2025; Accepted March 3, 2026; Published March 31, 2026
Highlights
● Elevated red cell distribution width (RDW) (>14.65%) at intensive care unit admission independently predicts 30-day mortality in young patients with sepsis-associated encephalopathy (SAE) (hazard ratio=2.7, 95% confidence interval [CI]: 1.4-5.3; P=0.003), persisting after rigorous propensity score matching (352 pairs) and multivariable adjustment.
● RDW achieved an area under the curve of 0.760 (95% CI: 0.720-0.800), outperforming prior reports in elderly sepsis cohorts and underscoring its specificity for young SAE.
● RDW is a low-cost, routinely available biomarker. Its integration into risk stratification could enable early intervention in resourcelimited settings, challenging the paradigm of youth conferring low risk in SAE.
Research Article |Published on: 31 March 2026
[Perioperative Precision Medicine] 2026; 4 (1): 94-104
Yue Shu1,*, Chunyue Jia2,*, Aimin Jiang3, Shuya Jiang4
1School of Anesthesiology, Hebei North University, Zhangjiakou 075000, Hebei, China.
2The 92815 Unit Hospital, No.116 Xihu Village, Ningbo 315716, Zhejiang, China.
3Department of Urology, The First Naval Hospital of Southern Theater Command, Zhanjiang 524005, Guangdong, China.
4The Third Department of Hepatic Surgery, Eastern Hepatobiliary Surgery Hospital, Naval Medical University, Shanghai 200433, China.
* The authors contribute equally
Address correspondence to: Aimin Jiang, Department of Urology, The First Naval Hospital of Southern Theater Command, No. 40 Haibin 3rd Road, Xiashan District, Zhanjiang 524005, Guangdong, China. E-mail: czjiangaimin@smmu.edu.cn. Shuya Jiang, The Third Department of Hepatic Surgery, Eastern Hepatobiliary Surgery Hospital, Naval Medical University, No. 225 Changhai Road, Yangpu District, Shanghai 200433, China. E-mail: syjiang2018@163.com.
DOI: https://doi.org/10.61189/189238vryaia
Received December 10, 2025; Accepted February 28, 2026; Published March 31, 2026
Perspective |Published on: 31 March 2026
[Perioperative Precision Medicine] 2026; 4 (1): 105-109
Task Force on "Expert opinion on perioperative management of bleeding and coagulation in anesthesiology (2026 edition)"
Corresponding authors: Lize Xiong, Jianjun Yang and Wei Zhang.
Address correspondence to: Lize Xiong, Shanghai Fourth People's Hospital Affiliated to Tongji University Translational Research Institute of Brain and Brain-Like Intelligence, School of Medicine, Tongji University, No. 1279 Sanmen Road, Hongkou District, Shanghai 200434, China. E-mail: mzkxlz@126.com. Wei Zhang, Department of Anesthesiology, Pain and Perioperative Medicine, The First Affiliated Hospital of Zhengzhou University, No. 1 Longhu Middle Ring Road, Jinshui District, Zhengzhou 450046, Henan, China. E-mail: zhangw571012@126.com. Jianjun Yang, Department of Anesthesiology and Perioperative Medicine, The First Affiliated Hospital of Nanjing Medical University, No. 300 Guangzhou Road, Gulou District, Nanjing 210029, Jiangsu, China. E-mail: yjyangjj@126.com.
DOI: https://doi.org/10.61189/909222ormctb
Received September 2, 2025; Accepted September 10, 2025; Published March 31, 2026
Expert Consensus |Published on: 31 March 2026
[Perioperative Precision Medicine] 2026; 4 (1): 110-129
Haolong Zhang1,2,*, Jing Pan1,*, Zhijing Song1
1Clinical College of Traditional Chinese Medicine, Gansu University of Chinese Medicine, Lanzhou 730000, Gansu, China.
2The First Affiliated Hospital of Henan Medical University, Xinxiang 453100, Henan, China.
*The authors are co-first authors.
Address correspondence to: Zhijing Song, Clinical College of Traditional Chinese Medicine, Gansu University of Chinese Medicine, No. 35 Dingxi East Road, Chengguan District, Lanzhou 730000, Gansu, China. E-mail: songzhijing2020@163.com.
DOI: https://doi.org/10.61189/372252akozze
Received November 11, 2025; Accepted March 16, 2026; Published March 31, 2026
Research Article |Published on: 31 March 2026
[Perioperative Precision Medicine] 2026; 4 (1): 130-148