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Expert opinion on perioperative management of bleeding and coagulation in anesthesiology (2026 edition)

Task Force on "Expert opinion on perioperative management of bleeding and coagulation in anesthesiology (2026 edition)"


Corresponding authors: Lize Xiong, Jianjun Yang and Wei Zhang.  


Address correspondence to: Lize Xiong, Shanghai Fourth People's Hospital Affiliated to Tongji University Translational Research Institute of Brain and Brain-Like Intelligence, School of Medicine, Tongji University, No. 1279 Sanmen Road, Hongkou District, Shanghai 200434, China. E-mail: mzkxlz@126.com. Wei Zhang,Department of Anesthesiology, Pain and Perioperative Medicine, The First Affiliated Hospital of Zhengzhou University, No. 1 Longhu Middle Ring Road, Jinshui District, Zhengzhou 450046, Henan, China. E-mail: zhangw571012@126.com. Jianjun Yang, Department of Anesthesiology and Perioperative Medicine, The First Affiliated Hospital of Nanjing Medical University, No. 300 Guangzhou Road, Gulou District, Nanjing 210029, Jiangsu, China. E-mail: yjyangjj@126.com.


DOI: https://doi.org/10.61189/909222ormctb


Received September 2, 2025; Accepted September 10, 2025; Published March 31, 2026 

Abstract

With advancements in surgical techniques and increasing complexity of patients' underlying conditions, the management of perioperative bleeding and coagulation disorders has intensified. Clinical practice faces issues such as non-standardized monitoring, inconsistent management protocols for specific patient populations, and unclear thresholds for blood transfusion and hemostatic agent administration. Based on evidence-based principles and integrating the latest evidence since 2020, the task force developed this consensus, titled "Expert Opinion on Perioperative Management of Bleeding and Coagulation in Anesthesiology (2026 Edition)". Focusing on the entire perioperative process, it covered coagulation assessment and monitoring, indications for blood product transfusion, rational use of hemostatic agents, and individualized strategies for special populations, including patients on antithrombotic therapy and those undergoing cardiac, neurosurgical, orthopedic or obstetric surgery. It emphasized preoperative risk screening, intraoperative dynamic monitoring, and post-operative balance between hemostasis and thrombosis prevention. Clinical decision-making should integrate the patient's baseline condition, surgical type, and real-time monitoring results. This opinion aims to provide standardized, multi-disciplinary guidance, optimize management protocols, reduce transfusion-related risks and thrombotic complications, and ultimately enhance perioperative patient safety and improve outcomes.

Keywords: Perioperative period, Hemorrhage, Blood coagulation, Expert opinion

Cite

Task Force on "Expert opinion on perioperative management of bleeding and coagulation in anesthesiology (2026 edition)". Expert opinion on perioperative management of bleeding and coagulation in anesthesiology (2026 edition). Perioper Precis Med. 2026 Mar; 4 (1): 110-129. doi: 10.61189/909222ormctb

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