Endless possibilities in academia
Endless possibilities in academia
Chenglong Zhu1, Wenyun Xu1,2, Zui Zou1
1School of Anesthesiology, Naval Medical University, Shanghai 200433, China. 2Department of Anesthesiology, Second Affiliated Hospital of Naval Medical University, Shanghai 200003, China.
Address correspondence to: Zui Zou, School of Anesthesiology, Naval Medical University, 168 Changhai Road, Yangpu District, Shanghai 200433, China. E-mail: zouzui@smmu.edu.cn.
DOI: https://doi.org/10.61189/156428jxplrz
Received October 26, 2024; Accepted January 7, 2025; Published September 30, 2025
Many patients, such as those who are obese, are prone to hypoxia during anaesthesia induction, painless gastroenteroscopy, and ICU sedation, which can lead to severe organ damage [1]. The traditional nasopharyngeal airway can effectively alleviate this problem, but it also introduces complications such as epistaxis [2]. NaPSflex (Nasal Pharyngeal Set-flexible) is a novel nasopharyngeal airway set developed by our team, designed to address difficult airways safely and simply. It has been registered as a medical device in China (Zhejiang Medical Device Registration Approval No. 20232081212).
NaPSflex consists of a reinforced catheter, a spring core, a restrictive nose plug, and an adapter (Figure 1). The reinforced catheter has small holes underneath for ventilation. With an outer diameter of only 4 mm, it prevents nasopharyngeal compression damage during catheter retention. The catheter is made of a flexible material to reduce the risk of nasal mucosa abrasion. The spring core is flexible, allowing easy access to the nasopharyngeal lumen. The restrictive nose plug regulates the catheter’s depth into the nasal cavity and helps secure it in place. Additionally, the catheter can be connected to either a nasal cannula or an anaesthesia machine’s breathing line via the adapter for oxygenation.
Several randomized controlled studies, approved by the Ethics Committee of the Naval Medical University and currently in the process of data collection, may provide robust evidence of its safety and efficacy. We believe that the new nasopharyngeal airway set can be widely adopted by anesthesiologists due to its potential in airway management.
Letter to the Editor |Published on: 30 September 2025
[Perioperative Precision Medicine] 2025; 3 (3): 71
Rahul Kumar Chaudhary, Prajwal Bista*, Lalit Kumar Rajbanshi*, Kanak Khanal*
Department of Anesthesiology and Critical Care, Birat Medical College Teaching Hospital, Morang, 56613, Nepal.
*The authors contribute equally.
Address correspondence to: Rahul Kumar Chaudhary, Department of Anesthesiology and Critical Care, Birat Medical College Teaching Hospital, Tankisinuwari, Dharan Road, Morang, 56613, Nepal. E-mail: rahulkr9991@gmail.com.
DOI: https://doi.org/10.61189/655401cvkjpp
Received June 24, 2025; Accepted August 29, 2025; Published September 30, 2025
Highlights
● Anaphylaxis is a potentially life-threatening event during general anesthesia, with a rare incidence estimated at 1 in 10,000 to 1 in 20,000 cases.
● Neuromuscular blocking agents, antibiotics, and latex are the primary triggers of perioperative anaphylaxis, with rocuronium being one of the most commonly implicated drugs.
● Sugammadex is a valuable drug for reversing rocuronium-induced refractory anaphylaxis.
Case report |Published on: 30 September 2025
[Perioperative Precision Medicine] 2025; 3 (3): 72-75.
Yu Xiang, Jiameng Liu, Huan Li, Kecheng Zhai, Xingchen Yue, Shangping Fang
Anesthesia Laboratory and Training Center, School of Anesthesiology, Wannan Medical College, Wuhu 241002, Anhui Province, China.
Address correspondence to: Shangping Fang, Anesthesia Laboratory and Training Center, School of Anesthesiology, Wannan Medical College, No.22, Wenchang West Road, Lugang Street, Yijiang Dis trict, Wuhu 241002, Anhui Province, China. Tel: +86-19855362767; E-mail: 20180041@wnmc.edc. cn.
Acknowledgement: This work was supported by Anhui Province College Student Innovation and Entrepreneurship Project (S202310368027 and S202410368031).
DOI: https://doi.org/10.61189/843291jljiwm
Received December 12, 2024; Accepted February 14, 2025; Published September 30, 2025
Highlights
●Lipid metabolism and iron metabolism pathways are key biological pathways involved in ferroptosis.
● Ferroptosis exhibits complex crosstalk with other cell death forms in sepsis, with significant implications for dis ease pathogenesis and therapy.
● Ferroptosis plays a critical role in sepsis-related organ damage and prognosis.
● This review suggests directions and perspectives for treating ferroptosis and sepsis in the perioperative period.
Review Article |Published on: 30 September 2025
[Perioperative Precision Medicine] 2025; 3 (3): 105-115.
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