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rahulkr9991@gmail.comAnaphylaxis is a potentially life-threatening event during general anesthesia, with a rare incidence estimated at 1 in 10,000 to 1 in 20,000 cases.
Neuromuscular blocking agents, antibiotics, and latex are the primary triggers of perioperative anaphylaxis, with rocuronium being one of the most commonly implicated drugs.
Sugammadex is a valuable drug for reversing rocuronium-induced refractory anaphylaxis.
Open Accessrahulkr9991@gmail.comAnaphylaxis is a potentially life-threatening event during general anesthesia, with a rare incidence estimated at 1 in 10,000 to 1 in 20,000 cases.
Neuromuscular blocking agents, antibiotics, and latex are the primary triggers of perioperative anaphylaxis, with rocuronium being one of the most commonly implicated drugs.
Sugammadex is a valuable drug for reversing rocuronium-induced refractory anaphylaxis.
Neuromuscular blocking agents, particularly rocuronium, are a major cause of perioperative anaphylaxis. This report presents a rare and severe case of rocuronium-induced anaphylaxis in a 50-year-old woman undergoing an elective total laparoscopic hysterectomy at a tertiary care center in Eastern Nepal. Despite multiple doses of intravenous epinephrine, the patient did not achieve adequate hemodynamic recovery. However, a single bolus of sugammadex resulted in the rapid and complete resolution of symptoms. This case highlights the potential of sugammadex as a life-saving adjunct in treating NMBA-induced anaphylaxis that is unresponsive to standard inter ventions.
ISSN: 2957-5443
Volume 3, Issue 3
September 2025
Pages: 71-115
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