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Progress of near-infrared spectroscopy in cerebral blood oxygenation detection: A mini review

Xinrui Gui, Tingting Shi, Ruoyu Song, Rongguo Yan


School of Health Science and Engineering, University of Shanghai for Science and Technology, Shanghai 200093,  China.


Address correspondence to: Rongguo Yan, Department of Biomedical Engineering, School of Health Science and Engineering, University of Shanghai for Science and Technology, No. 516 Jungong Road, Yangpu District, Shanghai 200093, China. E-mail: yanrongguo@usst.edu.cn.


DOI: https://doi.org/10.61189/578860ievbid


Received October 19, 2023; Accepted November 28, 2023; Published December 31, 2023


Highlights

● Near-infrared spectroscopy (NIRS) technology transmits a beam of near-infrared light through a transmitter to the brain. 

● The changes in hemoglobin concentration and cerebral blood oxygen levels can be estimated using near-infrared light, by comparing the changes in light attenuation over time.

● This paper introduces the basic concept of measuring blood oxygen levels in brain tissue using NIRS technology, and presents the potential applications of the most recent developments in this field of study.

Abstract

In contrast to conventional oximeters, near-infrared spectroscopy-based brain tissue oximetry monitoring devices are capable of non-invasive, continuous, and real-time quantitative monitoring of cerebral oximetry parameters. Initially, these devices were utilized for intensive care or surgical monitoring of oxygen saturation. Due to the rapid advancement of optoelectronic sensing and measurement technologies over the past decade, the derived functional near-infrared brain imaging devices have been widely used in a variety of fields. This paper first introduces the basic principles of near-infrared spectroscopy-based cerebral oxygenation parameter detection, then focuses on the most recent developments in this field of study. Finally, a prospect on their future application in practical settings is also provided.

Keywords: Near-infrared spectroscopy, cerebral oximetry, non-invasive measurement

Gui XR, Shi TT, Song RY, et al. Progress of near-infrared spectroscopy in cerebral blood oxygenation detection: A mini review. Prog in Med Devices. 2023 Dec;1(3):175-182. doi: 10.61189/578860ievbid. 
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